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| 1.
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堀, 正 ; 野村, みどり
概要:
application/pdf<br />Departmental Bulletin Paper<br />The authors develop in this article a discussion on the present situation of measures for students with disabilities and measures against sexual harassment in national, public and
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private uilversities of Japan. The discussion proceeds on the basis of the data from a questionnaire addressed to the presidents of universities. All of 214 universities (45 national, 30 public, and 139 private) answered the questionnaire. About 60% of the universities admit disabled students in all of their faculties. The total number of the students with disabilities is 1044,91% are enrolled in private universities. Of these, students with physical disabilities are 70%. Most of the presidents show the necessity of both a public support system for students with disabilities and some measures against sexual harassment. Only six of the universities provide some measures against sexual harassment in all of their faculties, and three provide them on the faculty basis as well. Twentyseven universities, however, show their preparation. The increasing necessity for some measures against sexual harassment seems to be recognized from the fact that 55% of the universities consider "Much necessary" or "Comparatively necessary" as their response to the questionnaire. Some free opinions of the presidents support the necessity of measures against sexual harassment, but others find no necessity partly because any problem of this kind had never occurred in their universities. It seems that, university administrations assign a low order of priority to the issue of measures for students with disabilities and measures against sexual harassment.
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| 2.
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application/pdf<br />Departmental Bulletin Paper
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Yumin, SHANO ; NEZU, Kikuo
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application/pdf<br />Journal Article<br />An effective method for improving the signal-to-noise ratio from measurements of bearing housing vibration is presented.The method is based on the conventional adaptive noise cancelling
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(ANC) technique principle;it varies the main signal input and reference signal input.Since the main and reference inputs signals are collected at different times, this method is called asynchronous adaptive noise cancelling (AANC).It can improve the signal-to-noise ratio, as in the case of the detecting bearing faults when vibration signals of machinery are collected under low-frequency noise condition.In combination with AANC, statistical analysis, enveloping spectrum analysis techniques are used for detection of bearing fault and diagnosis.Experimental result has shown that these techniques can be made more effective only after AANC has reduced the background noise from the diagnostic signals.A new approach is proposed to the traditional fault detecting for self-aligning roller bearings when the shaft speed is low (250rpm) or high (1000rpm) condition.
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| 4.
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ISMAILOV, Murad ; DURST, Franz ; OBOKATA, Tomio
概要:
application/pdf<br />Journal Article<br />In the present study an LDA-based technique was applied to analyze details of
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a transient pipe-flow induced upstream by a fuel ingector. Due to highly accurate measurements of the instantaneous time series of velocity, fuel flow rate and pressure gradient were achieved. The pipe flow has been driven under an injection pressure of 0.6MPa at high injection frequencies of 25 and 50 Hz. The influence of the outflow orifice diameter, varid in range from 100 to 500 μm, on the transient pipe flow dynamics has also been described. The results show that transient behavior of rapid oscillating pipe flow is remarkably and systematically dependent on injection frequency and duration as well as on the orifice diameter.
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| 5.
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ISMAILOV, Murad ; ISHIMA, Tsuneaki ; OBOKATA, Tomio ; TSUKAGOSHI, Masayoshi ; KOBAYASHI, Kazumitsu
概要:
application/pdf<br />Journal Article<br />Time-dependent centerline velocity is measured using LDA-flow meter. Swirl inj
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ector at frequencies of 22 and 46 Hz generates oscillated flow under high-pressure from 4 up to 7 MPa. The encoded time-series of velocity is used to reconstruct the time-variable series of instantaneous flow rate and pressure gradient. Transient injection dynamics are analyzed to obtain basec characteristics of an injection system that will be able to be used for real time monitoring or active controlling of high-pressure gasoline injectors. The results obtained through analyzing the integrated mass rates within a cycle, indicate that a certain injection system is characterized by the flow rate constant γ which independent on injection duration and can be obtained from only accurate measurement of centerline velocity in the fuel transport pipeline. The present technique allows us to simplify the injection model and can be effectively adopted for practical employment on active and passive control with respect to gasoline direct injection engines.
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| 6.
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ISMAILOV, Murad ; ISHIMA, Tsuneaki ; OBOKATA, Tomio ; TSUKAGOSHI, Masayoshi ; KOBAYASHI, Kazumitsu
概要:
application/pdf<br />Journal Article<br />A high-pressure swirl type spray has been experimentally analyzed by using a phase Doppler anemometer(PDA). The experiment was performed with an injection pressure of 5 MPa and an injection
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frequency of about 46 Hz. The PDA data was obtained in a two-dimensional plane and arranged with the injection phase angle. The arranged data of mean velocity, Sauter mean diameter, and droplet number density were visualized by using commercial software. In this paper, the data were compared with the results of visualization. It is indicated by the experiment that the large velocity and large size droplets initiated from the injector with small spray angle at the beginning of the valve opening duration. This stage was called core jet. In the next stage called quasi umbrella spray, the spray developed with large spray angle. After closing the valve, the spray remains increasing its velocity and diameter. This was caused by the "post injection". Using PDA, the detailed feature of the spray can be discussed with high temporal resolution.
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| 7.
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HAMANA, Koei ; HAMANA, Hiroshi ; ITOH, Takashi
概要:
application/pdf<br />Departmental Bulletin Paper<br />The polyamine patterns of 21 strains of extremely halophilic archaebacteria, including three newly described genera, were examined. Agmatine as the major polyamine was found in
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all strains, while putrescine was found in many, but not all strains. These polyamine profiles are consistent with those of 47 strains of the extremely halophilic archaebacteria published previously, but are different from any other groups of archaebacteria. Thus, the polyamine profile of the halophilic archaebacteria serve as a useful chemotaxonomic marker within the archaebacteria.
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| 8.
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ISMAILOV, Murad ; ISHIMA, Tsuneaki ; TAKEDA, Chikashi ; OBOKATA, Tomio ; TSUKAGOSHI, Masayoshi ; KOBAYASHI, Kazumitsu
概要:
application/pdf<br />Journal Article<br />Transient temporal and spatial spray characteristics have been investigated. A
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kind of practical fuel injector with swirl nozzle was examined under variable injection duration within the range of 0.25 to 4.0 ms and injection pressure 5.0 and 7.0 MPa. The fuel spray was injected at a cycling frequency of 50 Hz in a room under normal atmospheric condition. Considered details of sub-millisecond transient dynamics were observed by using a high-speed video camera with temporal resolution of 24.69 μs(40500 frames / s). The results indicate that investigated spray consists of two incorporated flow fractions that are a core jet and a quasi-umbrella droplets spray simultaneously moving down and swirling in local cross-axis domains. Instantaneous transient values of axial and radial penetration were accurately evaluated and analyzed. It was observed that after actual injection a post-injection of fuel droplets occurs and the time-delay and lifetime of these droplets were systematically estimated.
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| 9.
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NAGAI, Ken-ichi ; KASUGA, Kunio ; KAMADA, Masaki ; YAMAGUCHI, Takao ; TANIFUJI, Katsuya
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application/pdf<br />Journal Article<br />Experimental results are presented on chaotic oscillations of a post-buckled reinforced beam subjected to lateral excitations.The beam is partially reinforced and is clamped at both ends.One end
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of the beam is arranged to move to an axial displacement by an elastic spring.The beam is deformed to a post-buckled configuration by the axial constraint.Under the post-buckled condition of the beam, chaotic responses are generated in specified regions of exciting frequency.The chaotic responses are examined by the Fourier spectrum, the Poincare projection and the maximum Lyapunov exponent.It is found among other tings that the chaos of the reinforced beam is mainly generated with the lower modes of vibration.The instability regions of chaos as well as the effect of inertia in the axial direction are also examined.
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| 10.
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Dobashi, Toshiaki ; Koizumi, Jun-ichi ; Kita, Rio
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application/pdf<br />Journal Article
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Tsuchiya, Jun
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application/pdf<br />Departmental Bulletin Paper<br />(1) The futurologist Alvin Toffler has shown that times have changed considerably from the agricultural revolution, to the industrial revolution, and to the products of the
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information/communication revolution. He analyzed a human beings' way of life in t
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| 12.
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Hamana, Koei ; Hamana, Hiroshi ; Shinozawa, Takao
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application/pdf<br />Departmental Bulletin Paper<br />Polyamines of the planarian, Dugesia tigrina and the leech, Haemadipsa zeylanica were analyzed by high-performance liquid chromatography. An uncommon polyamine, homospermidine,
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in addition to putrescine, cadaverine, spermidine, spermine and agmatine, was detected in the two organisms. Spermidine and spermine levels increased during regeneration in D. tigrina.
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| 13.
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Tomaru, Tadashi
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application/pdf<br />Departmental Bulletin Paper<br />In this paper we study the maximal ideal cycle on the minimal good resolution of a normal double point (X, o) defined by z^2=f(x, y) over the complex number field. We compare it to the
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fundamental cycle on the minimal resolution of (X, o). By using an argument of covering surface, we show that the ratio of coefficients of such both cycles on any exceptional component is always 1 or 2.
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| 14.
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Kondo, Toshihiko ; Kondo, Yoichi
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application/pdf<br />Departmental Bulletin Paper<br />Laborious analyses of whole genome require highly automated methods. Various methods previously developed for the classification of DNA fragments and genomic mapping, however,
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are difficult to be automated. We now report the development of new type of 'DN
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| 15.
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Taira, Kazuo
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application/pdf<br />Departmental Bulletin Paper<br />Trabecular meshorks (TMs) in hepatic sinusoidal endothelial cells of mouse, golden hamster, rat, guinea-pig, and rabbit were studied by scanning and freeze-fracture electron
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microscopy. TMs of examined all laboratory animals shared identical properties; TMs appeared on the cell surface as porous mounds; TMs were composed of varying numbers of anastomosing trabeculae; TMs were often merged with sieve plates; and, ridges and grooves connecting trabeculae were found on the floor membrane of TMs by freeze-fracture technique. TMs are derived from bunches of plasmalemmal invaginations and are involved in the rushed formation of sieve plate.
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| 16.
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Koyano, H ; Yamamoto, Y ; Saito, Y ; Yamanobe, T ; Komoto, T
概要:
application/pdf<br />Journal Article<br />The two crystal structures of poly(butylene-2,6-naphthalate) (PBN) have been determined by X-ray diffraction. The space group is <P(1)over bar> for both forms. The unit cell parameters of
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the B form are a = 4.55 Angstrom, b = 6.43 Angstrom, c (fibre axis) = 15.31 Angstrom, alpha = 110.1, beta = 121.1 and gamma = 100.6. The major difference in crystal structure between the A and B forms lies in the conformation of four methylene group sequences: <(SG)over bar TGS> for the A form and <TST(S)over bar T> for the B form.
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| 17.
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TAKEDA, Chikashi ; OHTA, Yuji ; ISHIMA, Tsuneaki ; ISHII, Kiyoshi ; OBOKATA, Tomio
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application/pdf<br />Journal Article<br />In order to measure flow velocity in the swirl and radial directions of a cylinder of an engine in practical use by means of a laser Doppler anemometer(LDA)through a small measuring window on the
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cylinder head, a back scattering fringe mode LDA is used. This LDA, however, can not be used to measure the velocity component in the axial direction of the cylinder. A single incidence-beam reference-mode LDA is developed to measure the velocity component along the optical axis of the LDA and is applied to measure the fluctuating flow velocity in the axial direction of the cylinder. Ensemble-averaged mean velocity and fluctuation intensity of the velocity as measured using the LDA show good agreement with those measured using the conventional fringe-mode LDA. Based on these results, it can be concluded that the reference-mode LDA is applicable to measurements of the flow velocity in the axial direction of the cylinder through the amall window on the cylinder head.
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| 18.
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石橋, 成太良 ; 中沢, 素邦 ; 俵谷, 武治 ; 吉田, 勝 ; 田村, 博信 ; 安達, 孝浩 ; 河口, 和寛 ; 岩倉, 啓子 ; 鷲見, 信好 ; 若林, 克己
概要:
application/pdf<br />Journal Article<br />A study was conducted to elucidate the mechanism of the increased thyroidal fu
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nction caused by oral administration of (±)-4-diethylamino-1,1-dimethylbut-2-yn- 1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21), a new drug for the treatment of urinary frequency and incontinence, in rats. Rats were given 500 mg/kg of NS-21 orally for 13 weeks. Rats were also given 500 mg/kg of the drug and 15 μg/animal of thyroxine (T_4) in order to assess the influence of T_4 treatment. NS-21 caused decreases in both total and free T_4 and increases in TSH and thyroxine uridine diphosphate glucuronyltransferase (T_4UDP-GT). Morphological examination of thyroid gland revealed stimulated follicles indicating heightened thyroidal function. The treatment of T_4 inhibited the stimulating effect of NS-21 on thyroid gland. These results show that the administration of NS-21 caused induction of T_4UDP-GT, which resulted in a compensatory stimulation of the thyroidal function by the increased secretion of pituitary TSH in response to increased blood thyroid hormone metabolism.
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| 19.
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Hamana, Koei
概要:
application/pdf<br />Departmental Bulletin Paper<br />Cellular polyamines of newly validated seventeen genera belonging to the two taxa of Gram-positive eubacteria were analyzed by HPLC. Brochothrix was devoid of polyamines and
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Globicatella and Dolosignarulum synthesized spermidine within the low G+C subgroup. Appreciable amounts of polyamines were not detected in the high G+C subgroup, Nocardioides, Aeromicrobium and Microlunatus, and the six genera Brachybacterium, Dermcoccus, Kocuria, Kytococcus, Nestenkonia and Luteococcus transferred from the genus Micrococcus. The coryneform Dermbacter produced cadaverine as the major polyamine. The actinomycetes Dermatophilus and Acidothermus, and anaerobic Bifidobacterium and Propionibacterium, belonging to the high G+C subgroup, had no polyamine synthetic ability.
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| 20.
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Tomaru, Tadashi
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application/pdf<br />Departmental Bulletin Paper<br />In [6] the author proved a formula for the fundamental genus of hypersurface singularities defined by Brieskorn type with three variables. In present paper we prove a more
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generalized formula for such singularities.
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| 21.
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Ito, Yoshikazu Z. ; Hiromachi, Sachiko ; Futawatari, Tamae ; Arai, Michiko
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application/pdf<br />Departmental Bulletin Paper<br />The efficacies of the steroidal antiandrogens chlormadinone acetat
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e (CMA), 17 α-acetoxy-6-chloro-2-oxa-4, 6-pregnadiene-3, 20-dione (TZP), and cyproterone acetate (CypA) for retardation of the growth of androgen-dependent human prostatic adenocarcinoma transplanted into nude mice (Honda tumor) were tested. CypA inhibited the growth of these tumors, while CMA and TZP did not affect the weight of cancer tissue at the doses examined. Serum levels of human prostatic acid phosphatase (PAP) in the tumor-bearing mice were very sensitive to the administration of antiandrogens, but the levels were not dependent on the changes in tumor weight. In contrast, human prostate-specific antigen (PSA) levels in the blood of the host mice were correlated with the weight of the tumors, and were independent of treatment with antiandrogens. Castration of the cancer-bearing mice resulted in reductions in all experimental parameters tested. The validity of PSA-secreting androgen-dependent human prostate cancer xenograft as a tool for screening of efficacious antiandrogens will be discussed.
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| 22.
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Taira, Kazuo
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application/pdf<br />Departmental Bulletin Paper<br />Subsurface cisternae, broad flattened sacs with varying numbers of fenestrae lying along the lateral plasma membrane, in murine hepatocytes were studied in thin sections and
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freeze-fracture replicas. Subsurface cisternae extended from pericanalicular to perisinusoidal areas of the cytoplasm of closely adjoining hepatocytes. Subsurface cisterna was made up of paired membranes, an inner cisternal membrane facing the cell interior and an outer cisternal membrane facing the lateral plasma membrane. The inner cisternal membrane was continuous in some locations with the endoplasmic reticulum. Subsurface cisterna was fenestra-rich at its portions underneath gap junctions. Subsurface cisternae appeared as anastomosing tubules at pericanalicular and perisinusoidal ends and joined with tubulovesicle networks seen in these cytoplasmic areas.
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| 23.
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Nakajima, Teruo ; Nakajima, Hiroko
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application/pdf<br />Departmental Bulletin Paper<br />Modern enterprises are apt to conduct a variety of business activities which are socially unacceptable. This report discusses the preservation of the global environment and information
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disclosure in modern society. We shall try tp describe changes in the socio-economic systems through the development of accounting information, corporate social reporting, information disclosure, etc. as follows : 1. Introduction 2. Accounting Information and Environmental Preservation 3. Environmental Preservation and Pollution and Environmental Taxes 4. Accounting Information and Environmental Audit 5. Accounting Information and Information Disclosure 6. International Contribution and Information Disclosure 7. Conclusion-life-cycle cost of a product-
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| 24.
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Suematsu, Michiko
概要:
application/pdf<br />Departmental Bulletin Paper<br />Shakespeare's theatrical dimensions have been noted and defined repeatedly by the various methodologies of stage-centred criticism. In line with this performanceoriented criticism,
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this essay attempts to examine Shakespeare's theatricality in relation to theatre space. The main concern is in what way his text owes its full realization to theatre space, and this issue will be discussed, citing some examples from the recent history of British Shakespearean productions.
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| 25.
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application/pdf<br />Departmental Bulletin Paper
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| 26.
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FUJISAWA, Nobuyuki ; KURIBARA, Toshiaki ; YOKOTA, Masaji ; TANA-AMI, Hiroshi ; WATANABE, Isao
概要:
application/pdf<br />Journal Article<br />Flow mixing in an air conditioning unit for automobiles is studied experimentally in a water tunnel to investigate the mixing mechanisms of flow inside the unit at various mix-door angles. Flow
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visualization is carried out using tracer particles and the fluorescent dyes illuminated by Ar laser sheet, which allows the simultaneous measurement of velocity and diffusion distributions of the flow mixing in the unit by analyzing the captured color images. The measurement of velocity and diffusion distributions indicates enhanced flow mixing at certain mix-door angles, which is caused by the intense mixing of the main flow and the recirculating heater flow downstream of the mix-door. The temperature distribution measured in a prototype unit supports the mixing characteristics observed in the model unit, suggesting the usefulness of the present image analysis.
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| 27.
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Dobashi, Toshiaki ; Koshiba, Tetsuya
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application/pdf<br />Journal Article
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| 28.
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Takezawa, Sanzo ; Iida, Yoshihiro
概要:
application/pdf<br />Departmental Bulletin Paper<br />The absorption spectrum of the (0,0) and (1,0) Lyman bands of H_2
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were investigated in the Argon matrix at liquid nitrogen temperature. Red shadings of the R(0), R(1) and P(1) lines were observed. There is theoretical calculation of LeRoy-Hutson intermolecular potential for the H_2-Ar dimer [J. Chem. Phys. 86:837-853, 1987]. The potential depth of the drmer D_e is 51.069cm^<-1> with about 30cm^<-1> zero point energy; the energy D_0=21cm^<-1> corresponds to the energy below the bound free state. The 21cm^<-1> (14 oK) is fairly lower than 78 oK (54cm^<-1>) of liquid nitrogen temperature. However, the population of the ground state of the dimer mostly should be mostly populated in the potential well of the dimer. The shading of H_2 lines to the long wavelength side indicates that the upper levels of the dimer have deeper potential well than that of the lower level in the dimer complex. The fact suggests that the upper state of the complex, H_2^*(2pσB ^1Σ^+_u)+Ar(3p^<61>S) may have the potential well with deeper depth than 50cm^<-1> it is estimated to be D_e=91～166cm^<-1> and D_0=61～136cm^<-1>.
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| 29.
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Hamana, Koei
概要:
application/pdf<br />Departmental Bulletin Paper<br />Polyamines of the nine genera of coryneform and related Gram-positive eubacteria were analyzed by HPLC. Authentic species of Microbacterium, Aureobacterium, Cellulomonas and
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Corynebacterium were devoid of polyamines. Arthrobacter species were divided into polyamine-absent, putrescine, cadaverine and putrescine-cadaverine types. Clavibacter contained putrescine and cadaverine. Spermidine was detected in some species of Brevibacterium, Exiguobacterium and Curtobacterium and diaminopropane in some Curtobacterium. Heterogeneous polyamine profiles were found in the three genera.
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| 30.
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Takezawa, Yasuko ; Takezawa, Sanzo
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application/pdf<br />Departmental Bulletin Paper<br />The problem on textual material and education method for non-English majors of college has been discussed intensively. We have attempted a method for the students of English
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classes majoring medical professionals, in College of Medical Care and Technology, Gunma University. The lack of interest in English classes of general education have stemmed from the dense curriculum with specialized subjects for medical professionals in addition to the hard preparation for the entrance examination. An experimental syllabus is stated on the basis of the fact that the most effective way to remove the precreated conceptional block toward English from the students is to select suitable topics which would attract their attention. Also, an experimental method attempted for the classes of English translation into Japanese will be discussed in combined with sight translation.
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| 31.
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Kako, Masako
概要:
application/pdf<br />Departmental Bulletin Paper<br />Child maltreatment is broken down to neglect, physical abuse, sexual abuse, emotional abuse and other types. The reported number of child abuse was over 2 million in a population of
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253 million in 1992 in the United States in contrast to 2,000 in 110 million in 1989 in Japan. Although the investigation is not complete in Japan, the rapid life style and culture may be creating more problems concerning violence, substance abuse, and break-down of the family than is actually seen. Unlike the United States, abusers in Japan are reported to be dominantly biological mothers than fathers. Because the risk factors on child abuse are linked to a child's physical and mental conditions, nurses need to recognize and approach effectively the risk factors of both children and abusers.
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| 32.
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Ito, Yoshikazu Z. ; Hiromachi, Sachiko ; Futawatari, Tamae ; Arai, Michiko ; Nakazato, Yoichi
概要:
application/pdf<br />Departmental Bulletin Paper<br />A tumorigenic epithelial-like cell line of rat prostate origin (PR4) was established in vitro. The cell line originated from a single cell of a previously established rat
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ventral prostate cell line, and has been serially subcultured more than 100 times over 5 years. The doubling time of the cells was 18 hours, and the saturation density was 5 x 10(6) cells/ml. Oval nuclei with dispersed chromatin and well developed cytoplasmic organelles were ultrastructural characteristics of the cells. The PR4 cells were transplanted into nude mice and the histology of the resulting tumors was neopolastic epithelial-like morphology that showed cells arranged in a sheet and cord structure with a solid pattern. Very high activities of prostatic acid phosphatase and beta-glucuronidase were observed in the cytosol of the cells. The PR4 cells did not respond to androgen. The use of the new cell line and other in vitro models of rat prostate as experimental tools for human prostatic cancer research was discussed.
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| 33.
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Nakajima, Teruo
概要:
application/pdf<br />Departmental Bulletin Paper<br />This report shows the expansion of accounting information attempted in the course of remarkable development of social information. And, this maintains how the " popularization
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of social information and accounting information " is necessary for the present day society. Individuals - Such as consumers, employees, local residents, etc. - as well as corporations should be able to blend into this new citizen's society. It should be understood that the "market economy" itself becomes unstable without the growth of this citizen's society. Analysis is carried on how fusion between social information and accounting information has developed : 1. Introduction. 2. Modern Society and social Information. 3. Corporate Social Accounting - Expansion of Accounting -. 4. Ecological Accounting - Accounting and Environmental Issues-. 5. Philanthropy and the Product Liability Act. 6. Conclusion - "Window Dressing - Unfair Accounting -" and "Doctor of Monetary Civilization" -. According to the above this report considers the popularization of social information and accounting and tries to provide a guideline for converting our society from a "growth - quantitative enlargement -" into a continuous "developing - qualitative improvement - one."
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| 34.
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Suematsu, Michiko
概要:
application/pdf<br />Departmental Bulletin Paper<br />In the English stage history of Shakespeare's A Midsummer Night's Dream, the fairies underwent decisive changes in their function. An imaginative presentation of the fairies
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is essential to any production of the Dream ; however, the past history of the productions proved otherwise. For example, after the Restoration, the presence of the fairies was required only for a decorative purpose. The romanticization of the play in the subsequent centuries further encouraged this trend until the redefinition of the fairies in this century finally redeemed their positive function within the play. This essay attempts to follow the process of the fairies' transformation on the English stage and see how the changing ideas of the fairies themselves incited this transformation.
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| 35.
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Takahashi, Kuniko
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application/pdf<br />Departmental Bulletin Paper<br />Parents' worry about consumption of sweets by their children and their beliefs in the popular opinions regarding sugar intake were investigated. One thousand eight hundred
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fifty nine adults having elementary school students completed a questionnaire on their views relating to sugar. Results indicated that 91% of parents worried about consumption of carbonated soft drinks and 83% were anxious about sweet snacks and chocolates. Over 80% of the subjects agreed that sugar was a cause of dental caries, adult disease and was effective in improving fatigue. In Japan, it is commonly believed that high sugar intake acidifies blood and then disolves calcim in bone. The myth of acidifyng blood was believed by 40% and disolving calcium was believed by 66% of the subjects. Parents who thought sugar caused attention deficit hyperactivity in children were 49%. Eight percent and 12% of parents agreed that sugar caused antisocial behavior in adulthood and juvenile deliquency in childhood respectively. Many parents worry about their children's consumption of sweets because of the many myths surrounding sugar. It is unfair to use these myths to prevent excessive sugar intake. Sugar intake reduction must be based on scientific rationale.
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| 36.
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An, Duong-Phuoc ; Nezu, Kikuo ; Akuto, Tsuneo
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application/pdf<br />Journal Article<br />This paper is concerned with the design of a slide mode control system from the view point of practical application. The problem is treated using the asymptotic reaching law method for
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assuring global stabilization, and the chattering phenomenon is alleviated by the saturated function of the boundary layer. The design algorithm is simple and applicable to a nonlinear system including disturbances and uncertainties with high robustness. Its effectiveness is proven by simulation as well as a bench experiment of a brushless motor vehicle.
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| 37.
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Akiyama, Shigeru ; Amada, Shigeyasu ; Yoshii, Tokuharu
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application/pdf<br />Journal Article<br />Various structural ceramics have been developed as heat-resistant materials. In some applications it is anticipated that they will be exposed to very-high-temperature environments of the order of
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thousands of degrees. Moreover, these ceramics are subjected to thermal loadings which change rapidly with time. Therefore, it is very important to investigate their thermal shock characteristics. In this report, the distributions of temperatures and thermal stresses of cylindrical-shaped Al_2O_3 ceramics under irradiation by laser beams are analyzed using the finite element method. Critical fracture curves are obtained from the relationships between spot diameters of laser beams and maximum values of thermal stresses for various power densities of laser beams. The irradiation experiments yield these critical fracture curves, and theoretical and experimental curves are in good agreement.
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| 38.
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Takezawa, Sanzo ; Takezawa, Nobuya
概要:
application/pdf<br />Departmental Bulletin Paper<br />The present paper reviews the potential benefits of employing tradable sulfur dioxide emission permits to reduce total SO_2 output by electric utility plants. SO_2 emission permits and
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other such instruments in a market based system should provide a cost effective approach to environmental protection.
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| 39.
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Sato, Kumiko ; Kara, Fumiko
概要:
application/pdf<br />Departmental Bulletin Paper<br />Some properties of Dirofilaria immitis acid proteinase were compar
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ed with mammalian cathepsin D and pepsin. The optimum pH of D. immitis acid proteinase was in the range of pH 2.8 to 3.4, whereas mammalian cathepsin D and porcine pepsin were 3.0 - 4.6 and around 2.0, respectively. When incubating in neutral pH at 50℃ for 10min, the activity of D. immitis proteinase was reduced to about 75% of the initial level, although that of cathepsin D did not change and that of pepsin was completely destroyed. D. immitis proteinase and cathepsin D hydrolyzed well human hemoglobin and myoglobin, whereas pepsin hydrolyzed human hemoglobin, bovine hemoglobin and cytochrome C. Pepstatin, a potent inhibitor of mammalian cathepsin D completely inhibited these three enzymes. However, the effect of pepstatin was abolished strongest on pepsin (5 × 10^<-8>). About 90% of the activity of pepsin was inactivated by diazoacetyl-DL-norleucine methyl ester (DAN) for 10min after beginning the reaction. Under the same condition, D. immitis proteinase was inactivated gradually, about 50% of the initial activity was inactivated 60min after the beginning of the experiment. However, cathepsin D was never affected by DAN even for after a 60min incubation. About 30% of the activity of pepsin was inactivated by first incubating the enzyme with 1.2-epoxy-3-(P-nitrophenoxy)-propane at 37℃ for 10 min, although D. immitis proteinase and cathepsin D were not affected. In conclusion, we confirmed that the D. immitis proteinase belongs to the aspartic proteinase group and is an intermediate type between cathepsin D and pepsin.
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| 40.
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Hamana, Koei
概要:
application/pdf<br />Departmental Bulletin Paper<br />The λ phage DNA and hog thyroid DNA after exposure to a hydroxyl r
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adical-generating system containing NADPH-cytochrome P-450 reductase and anthraquinones such as mitoxantrone (CL 232315) and CL 232468 lacked in intact DNA fragments, indicating DNA strand breaks. The mechanism of DNA scission by the drugs closely resembles that induced by adriamycin and mitomycin C. When isolated hog thyroid chromatin was exposed to the system containing mitoxantrone, fragmentation of chromatin DNA was not detected. DNase I digestion for chromatin DNA was inhibited by the presence of the anthraquinones, suggesting intercalation of the drugs to DNase I-sensitive DNA regions in chromatin without DNA strand breaks.
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| 41.
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Ito, Yoshikazu Z. ; Kuroiwa, Syunsuke ; Hiromachi, Sachiko ; Futawatari, Tamae ; Arai, Michiko
概要:
application/pdf<br />Departmental Bulletin Paper<br />Human prostatic cancer transplanted into nude mice (HONDA) was tre
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ated with nonsteroidal antiandrogen, flutamide (FLT) or steroidal antiandrogen, chlormadinone acetate (CMA), with the doses of 50 mg and 200 mg for 28 days, and with a 5 μg daily dose of gonadotropin-releasing hormone agonist, leuprolide (LEU), for 8 weeks separately. Administration of 200 mg of FLT showed the most significant inhibition of the tumor growth followed in decreasing order by 200 mg of FLT, and 50 mg FLT. Monotherapy with 50 mg of CMA showed no effect on the growth of the tumor, suggesting that FLT is more potent antiandrogen than CMA. However, there was no reduction of the tumor weight despite the treatment with these agents. Orchiectomy markedly reduced the tumor weight. The weight of seminal vesicles and ventral prostate of the host mice were reduced significantly after the treatment with these antiandrogens, suggesting that there was substantial suppression of endogenous androgen action in these organs. Notable reduction of serum human prostatic acid phosphatase in the tumor-bearing mice was observed. Monotreatment with LEU did not inhibit the tumor growth, indicating the impairment of pituitary-gonadal axis of the nude mice. There was no changes in the content of the androgen receptor in the tumor cells regardless of the treatment. These results indicate that inhibitory effects of the antiandrogens in this experimental system is by direct cellular action. Although orchiectomy indicates the total androgen blockade in the mice, the discrepancy between the continuous tendency of the tumor growth notwithstanding antiandrogen treatment and the suppression of the endogenous androgen action suggests that growth-promoting factors other than androgens exist in the cancer family.
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| 42.
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AKIYAMA, Shigeru ; AMADA, Shigeyasu
概要:
application/pdf<br />Journal Article<br />Structural ceramics are attracting attention in the development of space planes, aircraft and nuclear fusion reactors because they have excellent wear-resistant and heat-resistant
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characteristics. However, in some applications it is anticipated that they will be exposed to very-high-temperature environments of the order of thousands of degrees. Therefore, it is very important to investigate their thermal shock characteristics. In this report, the distributions of temperatures and thermal stresses of cylindrically shaped ceramics under irradiation by laser beams are discussed using the finite-element computer code (MARC) with arbitrary quadrilateral axisymmetric ring elements. The relationships between spot diameters of laser beams and maximum values of compressive thermal stresses are derived for various power densities. From these relationships, a critical fracture curve is obtained, and it is compared with the experimental results.
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| 43.
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Ohtake, Koichiro
概要:
application/pdf<br />Departmental Bulletin Paper<br />Let R and S be rings with identity, and Mod-R and S-Mod the catego
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ry of unital right R- and left S-modules, respectively. Also let A and B be full subcategories of Mod-R and S-Mod such that A〓R and B〓S and both are closed under finite direct sums, submodules and epimomorphic images. We will find conditions in order that there exists a duality between Giraud subcategories of A and B. As an application of this we will obtain a general result of [8] about Morita duality between Grothendieck categories.
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| 44.
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Murasaki, Takeaki
概要:
application/pdf<br />Departmental Bulletin Paper
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| 45.
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Amagai, Kenji ; Hashimoto, Hiroyuki
概要:
application/pdf<br />Journal Article<br />Constitutive equations regarding the drift flux model for a multiphase flow consisting of molten material and its solidified particles were thermodynamically derived under a condition of local
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quasiequilibrium. The basic equations, including the conservation equations and the constitutive equations for the multiphase flow, were expressed in dimensionless forms. The theory developed here confirmed that the temperature fields closely depended on the Lagrangian derivative of the solid fraction accompanying the latent heat effect, and was characterized by the Stefan number. It was also suggested that the simplified basic equations corresponding to the phase equilibrium diagram were useful in the analysis of multiphase flow with solid-liquid phase change.
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| 46.
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Kashimoto, Hiroshi ; Nagaya, Kosuke ; Shiraishi, Akio
概要:
application/pdf<br />Journal Article<br />This paper presents a method for solving the dynamic stress concentration problem of inhomogeneous rods having two-dimensional arbitrary curvature, variable cross section and infinite length
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subjected to in-plane bending wave excitation. In this analysis, the exact solution of the equilibrium equations for curved rods has been obtained, and the transfer matrix, based on the exact solutions with consideration of the inertia forces has been derived. At discontinuous sections, solutions of curved and straight rods have been connected by adjusting the boundary conditions. As examples, stress concentration factors in circular, elliptical and parabolic arc rods with variable cross sections have been calculated.
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| 47.
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47. Influence to the Quantum Defect of H_2 Rydberg States in the II^- - II^- Homogenous Perturbation
Takezawa, S. ; Iida, Y.
概要:
application/pdf<br />Departmental Bulletin Paper<br />When a localized perturbation takes place in the Rydberg series, t
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he quantum defect δn of the series shows a value deviated from the normal one of the series. In the homogenous perturbation between Rydberg states (II^-) the electro-vibronic levels show an appearance without any perturbations, even if it exists, because of having the similar rotational constants. The plots of the rotaional levels T(υ, J) against J(J+1) are not crossed, but parallel. The energy shifts are similar in the each levels. In such cases we, therefore, have to detect the existence of localized perturbation from the abnormal quantum defects in the series or deviated rotational constants in the Rydberg bands. Thus studies on the quantum defect is quite important as an evidence of a localized perturbation. In this work we investigate relation between energy spacing, internuclear distance and quantum defect, by using a typical example of the interaction in the 5pπ^1II^-_u (υ=2) and 7pπ^1II^-_u (υ=1) in H_2. Also we discuss an autoionization effect of perturbed rotational levels in the autoionization area.
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| 48.
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Uemiya, Hideyuki
概要:
application/pdf<br />Departmental Bulletin Paper<br />Formation of the central and stomatogastric nervous system in late stages is described. The frontal ganglion is originated from the thickening part of the stomodaeal wall. The
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neuropile of the lobe 1 in the protocerebrum differentiates into three parts, i.e. the medulla interna, medulla externa and lamina ganglionalis. In Stage 8, the cephalization completes, and the cerebral ganglia acquire the definitive position. The lobe 3 is thought to represent the ganglion of the preantennal segment. The head in this species is composed of the acron plus six segments.
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| 49.
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Ito, Yoshikazu Z. ; Hiromachi, Sachiko ; Shirahama, Akiko ; Arai, Michiko ; Futawatari, Tamae ; Nakazato, Yoichi a6fda3e0d86bb4578a02926de06c4502
概要:
application/pdf<br />Departmental Bulletin Paper<br />Combination treatment with human natural interferon-alpha (IFN-alpha) and natural interferon-gamma (IFN-gamma) markedly reduced the weight of metastatic human renal cell carcinoma
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(RCC) transplanted into nude mice. Monotherapy with IFN-alpha or IFN-gamma inhibited the tumor growth without reducing the tumor weight. After combination treatment with IFN-alpha and-gamma, histological features showed notable reduction in the number of mitotic tumor cells and appreciable fibrosis in the stroma of the tumor. Infiltration of macrophages in the tumor was sparse. The results suggested that the antitumor activity of the IFNs is by direct cellular action. The general condition of tumor-bearing mice treated with IFN-alpha and-gamma was well retained, while marked emaciation was observed in the untreated tumor-bearing animals. The finding indicated that the combination treatment of RCC with IFN-alpha and-gamma may reduce the tumor burden of host mice.
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| 50.
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Kako, Masako ; Kondo, Yoshie ; Seto, Masako ; Shoda, Michiko ; Sato, Kumiko
概要:
application/pdf<br />Departmental Bulletin Paper<br />We investigated the prevalence of anti-Toxoplasma antibodies in the general population, and among unmarried young women who were freshmen in the College of Medical Care and
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Technology, Gunma University. The frequency of anti-Toxoplasma antibodies among general population increased gradually from 0.7% in the under 19 year age group to 35% in the 80 to 99 year age group. Up to the age of 29 years (young age group), 2.8% had the antibody, between the age of 30 to 59 years (middle age group) 18.6%, and from the age of 60 and over (old age group) 34.2%. However, the level of titers in the young age group was higher than the others. The finding indicates recent infection of Toxoplasma gondii in the young age group. In the study of the year-to-year changes among freshmen from 1987 to 1992, there has been an obvious decrease in frequency. Nineteen out of 472 subjects (4.0%) had the antibody in 1987, and 12 out of 503 (2.4%) in 1992. The result indicates the risk of primary infection among young people.
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