妊婦免疫能の変動

フォーマット:

論文

責任表示:

阿久沢, 由紀 ; 甕, その子 ; 関口, 三郎 ; 竹沢, 和男 ; 中村, 正江 ; 植原, 奈美子 ; 森, 初恵 ; 杉田, 光章 ; 新部, 万理子 ; 三石, 俊美 ; 倉茂, 達徳

言語:

日本語

出版情報:

群馬大学医療技術短期大学部, 1994-03-31

著者名:

阿久沢, 由紀

甕, その子

関口, 三郎

竹沢, 和男

中村, 正江

植原, 奈美子

森, 初恵

杉田, 光章

新部, 万理子

三石, 俊美

倉茂, 達徳

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掲載情報:

群馬大学医療技術短期大学部紀要

ISSN:

0389-7540      

巻:

14

開始ページ:

107

終了ページ:

114

バージョン:

VoR

概要:

application/pdf<br />Departmental Bulletin Paper<br />We studied in this paper the effects of pregnancy on nonspecific immunity of neutro-philes and specific immunity of T-lymphocytes. The number of neutrophiles increased and that of lymphocytes conversely decreased during pregnancy. The phagocytic activity of neutrophiles derived from pregnant woman was enhanced by the autoserum as same as that derived from normal non-pregnant woman. By the … contrast, the lymphocytes derived from pregnant woman showed low blastogenic respons iveness to Con A. The sera from pregnant women remarkably suppressed the blastogenic activity of lymphocytes prepared from both normal and pregnant women. Moreover, the lymphocytes from pregnant woman was much more sensitive to suppression by the serum fact or as compared with the lymphocytes from non-pregnant woman. The suppression by the serum was not due to cortizole that increased in the serum during pregnancy. These results suggest that specific cellular immunity of T-lymphocytes was suppressed to avoid fetal rejection and that nonspecific immunity of neutrophiles was enhanced to escape microbial infections during pregnancy. 続きを見る