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論文 |
論文
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Nagai, Takashi ; Imamura, Makoto ; Negishi, Tetuo ; Mori, Masatomo
概要:
application/pdf<br />Journal Article<br />A 49-year-old woman was admitted because of hyperglycemia. On a delivery at age 29 iron deficiency anemia was indicated. She was injected with 40mg of saccharated ferric oxide every two
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weeks until age 40. At age 35 menopause occurred. Serum ferritin increased (4,300ng/ml). An abdominal computed tomogram (CT) showed increased hepatic CT density. Iron deposition in the parenchymal cells of the liver was shown in a biopsy specimen. Secondary hemochromatosis was diagnosed. Her gonadotropin release decreased. After 30 months serum ferritin had decreased gradually to the normal range after daily 1,000mg injection of deferoxamine mesilate. Although the hepatic CT density decreased, gonadotropin release and insulin release were not improved.
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| 2.
論文 |
論文
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Nagai, Takashi ; Negishi, Tetuo ; Imamura, Makoto ; Mori, Masatomo
概要:
application/pdf<br />Journal Article<br />A 43-year-old diabetic woman was admitted in the 15th week of her first pregnancy. When HbAlc levels were 8.2%, we began diet therapy and continuous subcutaneous insulin infusion (CSII)
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therapy. The HbAlc levels subsequently ranged from 6.2 to 6.7%. She was delivered without complications of a healthy male infant (3120g) in the 38th week. Metformin was then administered. Six months later she was diagnosed as being in the 21st week of pregnancy. We changed from metformin to CSII therapy immediately. The HbAlc levels had ranged from 6.0 to 6.4% before the CSII therapy and from 5.8 to 6.3% after the CSII therapy during the entire second pregnancy. A macrosomia delivery (4070g) occurred in the 37th week. Although glycemic control was better during the 2nd pregnancy than the 1st pregnancy, metformin use until the 21st week may have induced macrosomia.
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