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| 1.
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論文
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Ogawa, Masaru ; Yokoo, Satoshi ; Yamaguchi, Takahiro ; Suzuki, Keisuke ; Makiguchi, Takaya
概要:
Journal Article<br />Background & Aims: The purpose of this study is to identify the clinical and immunohistological fac
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tors that inhibit bone healing after extirpation of extensive radicular cysts and endodontic microsurgery-microscopic apicoectomy, and utilize these factors as predictors of treatment outcome. Methods: Endodontic microsurgery-microscopic apicoectomy was performed in 26 patients. Outcomes were evaluated based on clinical signs and radiographs. Expression levels of cytokines (IL-1β, TNF-α, RANKL) in the cyst epithelium and subepithelial connective tissue were also investigated. Results: The success rate was 88.5%. The radiological reduction rate was ≥75% in 16 patients (good bone healing) and <75% in 10 (poor bone healing). In clinical analysis, penetrating bone defects and the site (maxilla) showed significant differences between the two groups (P<0.05). In immunohistochemical analysis, expression of IL-1β and TNF-α showed significant differences between the two groups (P<0.05). Conclusions: Penetrating bone defects, inflammation, and a maxillary site are prognostic factors for a poor outcome after treatment of extensive radicular cysts. Endodontic microsurgery-microscopic apicoectomy is a new technique for treatment of an extensive radicular cyst, and this study is the first to identify factors that influence the outcome after extirpation of the cyst.
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| 2.
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論文
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Kanbe, Tomoyuki ; Yokoo, Satoshi ; Ogawa, Masaru ; Takayama, Yu ; Gomi, Akinori ; Makiguchi, Takaya
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Journal Article
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| 3.
論文 |
論文
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Kanbe, Tomoyuki ; Yokoo, Satoshi ; Ogawa, Masaru ; Takayama, Yu ; Gomi, Akinori ; Makiguch, Takaya
概要:
Journal Article<br />Background& Aims:The purpose of this study was to investigate changes in facial morphology after partialmaxillectomy and recovery after dento-maxillary prosthesis placement. Methods:For facial morphology
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measurements,the non-contact 3-dimensional(3D)digitiser and the analytical software were used for 21 patients withdefects classified into Class I or II of the Aramany classification. Results:It was quantitatively demonstrated thatfacial deformities resulting from partial maxillectomy were due to concavities from the subnasal point to thementolabial groove in the vertical range,and from the region around the nasal alar to the anterior cheek in thelateral range.Facial features anterolaterally expanded on the defected side in volume with the prosthesis.Facialdisfigurement extended to the lower face,and improvement of these deformities was also observed with theprosthesis.Using the non-contact 3D digitiser,the direction and amount of movement of the facial componentswithin the mid-and the lower face regions were 3-dimensionally determined,enabling rapid and accurate identificationof facial deformities,and recovery of the facial morphology with prosthesis. Conclusion:This is the first studyto analyse of prosthesis-induced changes in facial morphology after partial maxillectomy with a non-contact 3D digitiser.
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