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Richard Rorty
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edited by James C. Kaufman, Robert J. Sternberg
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edited by Howard Marchitello
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| 4.
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図書
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Don Mitchell
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図書
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edited by Barry Smart
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図書
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Barbara Kirshenblatt-Gimblett
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図書
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author-editor Sue Golding
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| 8.
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論文
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Ito, Yoshikazu Z. ; Hiromachi, Sachiko ; Futawatari, Tamae ; Arai, Michiko ; Nakazato, Yoichi
概要:
application/pdf<br />Departmental Bulletin Paper<br />A tumorigenic epithelial-like cell line of rat prostate origin (PR4) was established in vitro. The cell line originated from a single cell of a previously established rat
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ventral prostate cell line, and has been serially subcultured more than 100 times over 5 years. The doubling time of the cells was 18 hours, and the saturation density was 5 x 10(6) cells/ml. Oval nuclei with dispersed chromatin and well developed cytoplasmic organelles were ultrastructural characteristics of the cells. The PR4 cells were transplanted into nude mice and the histology of the resulting tumors was neopolastic epithelial-like morphology that showed cells arranged in a sheet and cord structure with a solid pattern. Very high activities of prostatic acid phosphatase and beta-glucuronidase were observed in the cytosol of the cells. The PR4 cells did not respond to androgen. The use of the new cell line and other in vitro models of rat prostate as experimental tools for human prostatic cancer research was discussed.
続きを見る
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| 9.
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図書
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Arjun Appadurai
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| 10.
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図書
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Andrew Feenberg
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